What are Phytoalexins?
Phytoalexins are bioactive molecules that have a special ability to fight off bacteria, fungus and parasites.
The phytoalexins produced by red sorghum are especially unique. A concentrated, bright red, they accumulate in certain areas of the plant, like the leaf sheath, turning the small areas of the plant bright red.
How potent is it?
It has 80 to 100 times higher antioxidant capacity than other botanical extracts!
What form does 3-Daxin come in?
3-Daxin Sorghum Bioflavonoid Complex is delivered as a water-soluble, shelf-stable, ultrafine powder.
Science
The Plant
Plants don’t have immune systems. But over millions of years, they’ve evolved to stay healthy and protect against stress and attack.
Red Sorghum – like other types of higher plants – has the ability to produce complex botanical compounds called phytoalexins that provide defense against a range of pathogens and parasites.
Discovering the plant’s components health benefits
For millenia, our ancestors collected the most intensely colored parts of the plant, using the bright red extracts for herbal teas and as preservatives, and in traditional medicine and cooking.
We’ve learned a lot since then about plant biochemistry – and it turns out that the compounds that give red sorghum that intense color are bioactives responsible for keeping the plant itself healthy. And a huge body of research shows that these flavonoids and polyphenols have wide-ranging health and therapeutic benefits for us as well.
The challenge is that the plant only produces enough of these compounds to keep itself healthy – not enough to justify commercial extraction – until now.
RedLeaf was founded following the discovery of a rare natural mutation in this defense mechanism at University of Kentucky in 2009. This natural variation causes our patented RedNatural™ varietal to produce these compounds at such high levels the plant leaves turn red to maroon to purple. Developed over more than a decade using traditional plant breeding techniques, RedNatural™ produces these rare, valuable phytoalexisins at levels 2000 times higher than other variants. We’ve finally unlocked access to an extraordinary new extract.
Composition of the Extract
Starting with our unique RedNatural™ sorghum, RedLeaf uses a proprietary extraction process to produce a botanical extract we call 3-Daxin.
3-Daxin is also the first commercial source of 3-deoxyanthocyanidins, a rare and ancient class of botanical polyphenol typically only found in certain flower petals and ferns.
Bioactivity
Oxidative stress, inflammation, and immunity are three fundamentally interconnected biological processes.
Our cells have developed complex and fine-tuned systems to rapidly respond to external stresses and internal failures – and just as importantly, return to homeostasis and balance.
There’s a misconception that inflammation itself is bad. Inflammation is essential in mounting an immune response and recovering from illness or injury – but inflammation also creates oxidative stress that can damage proteins, DNA and cell structure, or accelerate cell death.
RedLeaf has shown distinctive ability to drive improved function – reducing oxidative stress and suppressing inflammation, while strengthening markers of immune health and readiness:
Potent Antioxidant
has unmatched ability to combat oxidative stress through multiple cellular mechanisms
• Neutralized 98.5% of theoretical maximum of oxidative stress in stressed cells; More potent than pure quercetin, 2x more potent than resveratrol, 20X epicatechin
• Up regulates natural cellular defenses against stress and damage (the NRF2 stress response)
• Unique catalase like activity – the ability to neutralize cellular superoxides like hydrogen peroxide
Shuts down
inflammation
for potent suppression of inflammatory cytokines – the signaling molecules that cause damaging inflammation
Near total suppression of TNF-alpha, IL6, IL8 in multiple inflammation models
Strengthens
immunity
by increasing levels of key messaging molecules responsible for the adaptive immune response
Significant and dose-dependent increase in key immune growth factors and markers, interleukin-2 and CD25, in activated T-cells
The science behind it
Headlines & studies:
RedLeaf’s sorghum extract drives dose-dependent increase in CD25
Inflammatory cytokine reduction in PBMCs
Flavonoid content and antioxidant capacity as compared with other botanical extracts commonly used in cosmetics
See the science behind it
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